2. Signaling Pathways
  3. Adhesion G Protein-coupled Receptors (AGPCRs)

Adhesion G Protein-coupled Receptors (AGPCRs)

Adhesion G Protein-coupled Receptors (AGPCRs)

 

Adhesion G Protein-coupled Receptors (AGPCRs) Related Products (3):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-16950A
    (E/Z)-4-Hydroxytamoxifen
    		Activator 99.62%
    (E/Z)-4-Hydroxytamoxifen (Afimoxifene) is a racemic compound of (Z)-4-Hydroxytamoxifen and (E)-4-Hydroxytamoxifen isomers. (E/Z)-4-Hydroxytamoxifen is a selective estrogen receptor modulator with mixed estrogenic and antiestrogenic activity, which is also an active metabolite of Tamoxifen (HY-13757A). (E/Z)-4-Hydroxytamoxifen is an agonist of the G protein-coupled estrogen receptor (GPER) with relatively low affinity (100-1000 nM). (E/Z)-4-Hydroxytamoxifen is promising for research of cyclical mastalgia, such as breast pain, tenderness, and nodularity.
    (E/Z)-4-Hydroxytamoxifen
  • HY-P10365
    VPM-p15
    		Agonist 98.18%
    Vmm-p15 is a peptide agonist optimized for the adhesion G protein-coupled receptor GPR64 (also known as ADGRG2 or HE6). The affinity of VPM-p15 with GPR64 is significantly higher than that of the original p15 peptide. The cAMP level induced by VMM-P15 increased significantly, activated GPR64, and triggered downstream Gs, Gq, and G12/13 signaling. VPM-p15 can be used to study the activation mechanism of adherent GPCR family members.
    VPM-p15
  • HY-P3942
    SDP116
    		Inhibitor 98.65%
    SDP116 is a synthetic Stachel-derived peptide of GPR116 Stachel peptide. SDP116 has ADGRF5 agonist effect.
    SDP116